PGT- A : End your struggle to conceive
Preimplantation genetic testing for aneuploidy (PGT-A) is a specialized genetic testing procedure that is used to detect chromosomal abnormalities in embryos created through in-vitro fertilization (IVF) before they are implanted into the uterus. PGT-A is used to identify embryos that have the correct number of chromosomes, also known as euploid, and those that have an abnormal number of chromosomes, also known as aneuploid.
During PGT-A, a small number of cells are removed from an embryo and analyzed for chromosomal abnormalities. This allows doctors to select the most viable and healthy embryos for implantation, increasing the chances of a successful pregnancy. PGT-A is a boon for couples who have had multiple failed IVF cycles or for those who are at a higher risk of having a child with a chromosomal disorder such as Down syndrome.
PGT-A is Recommended For:
- Reduced risk of miscarriage: Embryos that have chromosomal abnormalities are more likely to result in miscarriage. By identifying and discarding these embryos, PGT-A reduces the risk of miscarriage.
- Identifying Genetic Disorders: PGT-A can also be used to identify embryos that carry genetic disorders, allowing couples to make informed decisions about family planning.
- Advanced Reproductive Age: As women age, the risk of having a child with chromosomal abnormalities increases. PGT-A can help identify chromosomally normal embryos in women of advanced reproductive age, increasing the chances of a successful pregnancy.
- Recurrent IVF failure: For couples who have had multiple failed IVF cycles, PGT-A can help identify chromosomally normal embryos that may have been overlooked in previous cycles.
Benefits of PGT-A
- Increases the chance of a healthy pregnancy across all age groups-The risk of having a pregnancy with a chromosome abnormality increases as females age.
- Reduces the likelihood of miscarriage- Embryos are chosen primarily on their visual quality – which cannot distinguish chromosomally normal embryos from abnormal ones. IVF cycles that do include PGS enable the identification of embryos with normal chromosomes, and are more likely to result in a pregnancy that leads to a healthy baby.
- Reduces time between IVF cycles-Preimplantation Genetic Screening reduces time between IVF cycles by allowing the identification of a normal embryo as soon as possible. If a woman goes through an IVF cycle and a normal embryo is not identified, she can start her next cycle right away.
- Allows for confident single-embryo transfer, which helps avoid the added health complications associated with twin or triplet pregnancies-PGS allows for single-embryo transfer by identifying the embryo that has the best chances of implanting and leading to a healthy child. Multiple pregnancies can cause increased risk for complications during pregnancy, such as preterm birth, abnormal placental function, preeclampsia, and others.