Recurrent Pregnancy Loss (RPL)

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Recurrent Pregnancy Loss (RPL)

Recurrent pregnancy loss (RPL) is the condition in which a couple experiences 3 consecutive pregnancy loss before 20 weeks from the last menstrual period. However, there is a lack of consensus regarding the number of miscarriages to term it as RPL.

Recurrent Pregnancy Loss is also referred to as habitual abortion or recurrent miscarriage which affects almost 1% of the couples trying to conceive. Also, RPL is found in 50% of the couples in whom no obvious pathology is identified.

RPL Causes

The most common causes of Recurrent Pregnancy Loss include:

  • Genetic causes
  • Anatomic causes
  • Infectious causes
  • Hematologic causes
  • Environmental causes

Out of all the above causes, more than half of the early pregnancy losses are associated with chromosomal abnormalities.

SOI Expertise

SOI uses molecular genetic technology to provide needy couples with detailed genetic information about RPL causes and risk factors. Further, the genetic analysis offers couples with reduced risks in future reproductive choices. However, the method of diagnosis varies depending on the period of pregnancy.


Q. How many women suffer from RPL?

Pregnancy loss is a common occurrence with nearly 15% pregnancies leading to miscarriages. However, Recurrent pregnancy losses which consider 3-consecutive miscarriages is believed to affect nearly 2% of women.

Q. How long must one wait to conceive again following a pregnancy loss?

Women should try for another pregnancy following one normal menstrual cycle.

Q. Does pregnancy loss increase risk for more future miscarriages?

For most women, pregnancy loss is a one-time occurrence. But yes, a pregnancy loss does increase the risk factors for multiple miscarriages.