HLA Matching

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HLA Matching

What is HLA?

HLA or Human leukocyte antigen is our health DNA, which is responsible for strengthening our immune system.

HLA matching is used in conjunction with PGD for healing children with genetic illnesses such as thalassemia, leukemia, Wiskott Aldrich syndrome. It is an ideal option for couples who can’t find a suitable donor in close relatives.

How HLA Matching Works?

HLA Matching works with the aid of stem cell transplantation from a sibling born out of IVF.

Couples undergo the IVF process, and a PGD (PGD (Pre Genetic Diagnostics) is done during fertilization of the embryos for checking HLA compatibility with the sick sibling.

Upon successful IVF motherhood, the stem cells from the chord of the resulting child are used to cure the sick sibling. This process is known as “HLA typing in embryos.”

Other than curing genetic conditions in siblings, HLA matching can also be used to ensure a safe and healthy IVF baby for couples carrying genetic disorders.

SOI Expertise

SOI offers highly advanced HLA Matching treatment. Embryo compatibility, quality, and suitability are identified through detailed testing. We perform a comprehensive analysis of the genetic information using blood samples of couples and their sick children to ensure a safe and successful pregnancy.


Q. What are HLA Markers?

HLA Markers are protein maps in our body cells. Our immune system uses these protein maps to identify the cells that belong to our body. These markers are used during HLA matching for checking the compatibility of sick siblings with potential donor siblings.

Q. How long does the MLA Matching process take?

The HLA test results take no more than 1 to 2 weeks. However, genetic preparations, including embryo development, selection, and transfer, can take approximately 3 weeks.

Q. What is the success rate?

CHances of success depend on several factors, including the total number and quality of embryos. As per studies, 25% of the embryos are expected to be HLA compatible with the sick sibling. However, this rate may vary depending on specific genetic disorders.